COMPOSITION

Panpot 20 mg

Each enteric coated tablet contains 
Pantoprazole Sodium Sesquihydrate equivalent to Pantoprazole ....... 20 mg
 
Panpot 40 mg
 
Each enteric coated tablet contains
Pantoprazole Sodium Sesquihydrate equivalent to Pantoprazole........... 40 mg


DESCRIPTION

Pantoprazole is a proton pump inhibitor (PPI) that suppresses the final step in gastric acid production by covalently binding to the (H + / K +)-ATPase enzyme system at the secretory surface of the gastric parietal cell. This effect leads to inhibition of both basal and stimulated gastric acid secretion irrespective of the stimulus. The binding to the (H + /K +)-ATPase results in a duration of antisecretory effect that persists longer than 24 hours for all doses.
 
INDICATIONS

 Short-term treatment of erosive esophagitis associated with gastroesophageal reflux disease (GERD)
 Maintenance of healing of erosive esophagitis.
 Pathological hypersecretory conditions including Zollinger- Ellison Syndrome.

DOSAGE & ADMINISTRATION
Short-Term Treatment of Erosive Esophagitis Associated With Gastroesophageal Reflux Disease (GERD) and Maintenance of Healing of Erosive Esophagitis 40 mg given once daily for up to 8 weeks Pathological Hypersecretory Conditions Including Zollinger-Ellison Syndrome The recommended adult starting dose is 40 mg twice daily.
 
CONTRAINDICATIONS
Contraindicated in patients with known hypersensitivity to the formulation.
 
PREGNANCY CATEGORY: B
 
SIDE EFFECTS:
 Headaches
Diarrhea
Nausea
Flatulence
Abdominal pain
Insomnia
Rash
Burping
High blood sugar levels (hyperglycemia)
Vomiting
Abnormal liver function tests.