COMPOSITION

Each Capsule contains

Methylcobalamin 1500 mcg + Alpha Lipoic Acid 300 mg +Chromium polynicotinate 200 mcg + L-Selenium 100 mcg + Zinc Ascorbate 20 mg + Calcium D - Pantothenate 12.5 mg + Vit E 15 I.U + Vit B1 4.5 mg + Vit B2 5 mg + Vit B6 3 mg + Folic acid 1.5 mg


DESCRIPTION:

Methylcobalamin is a type of Vitamin B12. Vitamin B12 comes in several kinds including hydroxy-, cyano-, and adenosyl-, but only the methyl and adenosyl forms are active within the body. Methylcobalamin donates methyl groups to the myelin sheath that insulates nerve fibres and regenerates damaged neurons. In a B12 deficiency, toxic fatty acids destroy the myelin sheath but high enough doses of B12 can repair it.

Homocysteine has emerged as a strong and independent risk factor for heart disease and stroke, and is also connected to chronic diseases such as arthritis, Alzheimer's and diabetes. The clinical and therapeutic dose of Methylcobalamin along with folic acid and pyrodixine has been shown to reduce the homocysteine levels and reduce the risk of CVD & stroke.

Alpha LipoicAcid, chemicallyis 1, 2-dithiolane-3-pentanoic acid. It is a sulphur containing substance, which is readily converted from its reduced state, dihydrolipoic acid. It can be found in foods such as meats and spinach. It is readily absorbed in the blood stream and can also cross blood brain barrier. 

It functions as a cofactor for enzymes involved in conversion of energy from glucose and fats, Krebs cycle (metabolism of fats and carbohydrates). It is a powerful antioxidant and prevents cellular damage from free radicals thereby reducing oxidative stress. It increases production of glutathione, which helps dissolves toxic substances in liver. 

Folic acid (Vitamin B9), a member of the B-complex vitamins, is a water-soluble vitamin that is unstable in heat and light. Folic acid is required for DNA synthesis and cell growth and is important for red blood cell formation, energy production as well as the forming of amino acids. Folic acid is essential for creating haeme, the iron containing substance in hemoglobin, crucial for oxygen transport. It is important for healthy cell division and replication, since it is acts as a coenzyme for RNA and DNA synthesis. It is also required for protein metabolism and in treating folic acid anemia. Folic acid also assists in digestion, and the nervous system, and works at improving mental as well as emotional health.

Vitamin B6 is a water-soluble vitamin that exists in three major chemical forms: pyridoxine, pyridoxal, and pyridoxamine. It performs a wide variety of functions in our body and is essential for our good health. Vitamin B6 is needed for more than 100 enzymes involved in protein metabolism. It is also essential for red blood cell metabolism. The nervous and immune systems need vitamin B6 to function efficiently, and it is also needed for the conversion of tryptophan (an amino acid) to niacin (a vitamin).

Chromium amplifies insulin response. Zinc helps in regulation of insulin production by pancreatic tissues. Zinc is involved in the regulation of insulin receptor-initiated signal transduction mechanisms and insulin receptor synthesis. Vitamin E Significantly reduces LDL oxidation and decrease protein glycation in diabetics. Vitamin B1 prevents micro and macro vascular complications. Calcium D - Pantothenate has a synergetic action with ALA in the treatment of DPN apart from L-Selenium which is an anti-oxidant.
 
Rationale for the combination:
Methylcobalamin 1500 mcg
Folic Acid 1.5 mg 
Vit B6 3 mg
Regulates Homocysteine levels
Alpha Lipoic Acid 300 mg
Vit E 15 I.U
Reduces Oxidative Stress &
prevents Oxidation of LDL cholesterol
Chromium Polynicotinate 200 mcg Amplifies Insulin response
Zinc Ascorbate 20 mg Insulin Receptor Synthesis
Vit B1 4.5 mg Prevents Micro and Macro Vascular
Complications
L-Selenium 100 mcg Anti-Oxidant
Calcium D – Pantothenate 12.5 mg

 

Synergistic action with ALA in the treatment
of Diabetic Peripheral Neuropathy
Vit B2 5 mg

 

Anti-Oxidant

 

 

INDICATIONS
As an adjuvant

     In Type 1 and Type 2 Diabetes Management to Prevent Complications
     To Diet and Exercise in IGT Patients
     In the Treatment of Diabetic Peripheral Neuropathy
     In High Risk Group People who are Prone to Diabetes and Cardio-Vascular Disease
     To Address Nutritional Deficiencies
     To Enhance Immunity &
     To Prevent Frequent Infections

DOSAGE & ADMINISTRATION
1 capsule a day or as recommended bythe physician
 
CONTRAINDICATIONS
Hypersensitivity to any ingredient of the composition